ASCC3 Rabbit Polyclonal Antibody, 50ul Gene Synthesis It requires divalent metal ions

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

It also prevents telomere elongation by inhibiting the actions of telomerase

as well as in the control of gene transcription

The encoded protein is localized mainly in the cytoplasm| with some in the mitochondria| suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes

ASCC3 Rabbit Polyclonal Antibody, 50ul Gene Synthesis It requires divalent metal ionsThis gene encodes a protein that belongs to a family of helicases that are involved in the ATP dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants.