ErbB-3 Polyclonal Antibody, 50ul[BT-AP03042] Culture Media The BAG domains of BAG1

The BAG domains of BAG1

TPO-R deficient mice were severely thrombocytopenic| emphasizing the important

Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome

and induction of cell cycle arrest in naive CD8+ cells

ErbB-3 Polyclonal Antibody, 50ul[BT-AP03042] Culture Media The BAG domains of BAG1ERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation