Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody, 50ul[BT-AP05346] High Speed Micro-Centrifuges Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been identified from this gene

The protein encoded by FKBPL (FK506 binding protein like) has similarity to the immunophilin protein family

localizes to a region of the Y chromosome frequently deleted in infertile males

Bone morphogenetic protein 3 suppresses osteoblast differentiation

Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody, 50ul[BT-AP05346] High Speed Micro-Centrifuges Several alternatively spliced transcript variantsThis gene encodes a member of the tyrosine kinase and more specifically the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such it may play a role in anti viral immunity. A mutation in this gene has been