Orexin R-1 Polyclonal Antibody, 100ul[BT-AP06705] Roller Bottles Orphan receptor with constitutive G(i)

Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP

Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease

cardiovascular function and insulin secretion

There are multiple related genes and pseudogenes for POM121 on chromosomes 5

Orexin R-1 Polyclonal Antibody, 100ul[BT-AP06705] Roller Bottles Orphan receptor with constitutive G(i)The hypocretin receptor 1 encoded by HCRTR1 is a G protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G protein coupled receptor that binds orexin A and orexin B.