PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 100ul Mammalian Expression TLEs contain several WD-repeats implicated

TLEs contain several WD-repeats implicated in protein-protein interaction

Related pseudogenes have been identified on chromosomes 7 and 14

members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis

Interacts with GSK3B

PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 100ul Mammalian Expression TLEs contain several WD-repeats implicatedThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in