HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 50ul Drug Development and Evaluation This gene has been found

This gene has been found to have multiple copies on many chromosomes| some of which| if not all| represent different pseudogenes

Members of this family are characterized by long N-termini and multiple functional domains

Three transcript variants encoding two different isoforms have been found for ERAP1

C-C motif chemokine 4encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product

HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 50ul Drug Development and Evaluation This gene has been foundContains two independent C terminal transactivation domains NTAD and CTAD which function synergistically. Their transcriptional activity is repressed by an intervening inhibitory domain (ID). Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions activates the transcription of over 40 genes including erythropoietin glucose transporters glycolytic enzymes vascular endothelial growth factor and