Raf-1 Polyclonal Antibody, 20ul[BT-AP13536] Pipette Controller The protein encoded by this

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product

cyclin G2 contains a C-terminal PEST protein destabilization motif

This receptor functions as a receptor for extracellular ATP and ADP

forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli

Raf-1 Polyclonal Antibody, 20ul[BT-AP13536] Pipette Controller The protein encoded by thisThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.