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SOCS-2 Polyclonal Antibody, 100ul[BT-AP08441] Polyclonal Antibodies The encoded muscle-specific enzyme plays

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SOCS-2 Polyclonal Antibody, 100ul[BT-AP08441] Polyclonal Antibodies The encoded muscle-specific enzyme playsSOCS2 encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine inducible negative regulators of cytokine receptor signaling via the Janus kinase signal transducer and activation of transcription pathway (the JAK STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal transducing

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Description

The encoded muscle-specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP)

It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell

Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2

The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization

SOCS-2 Polyclonal Antibody, 100ul[BT-AP08441] Polyclonal Antibodies The encoded muscle-specific enzyme playsSOCS2 encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine inducible negative regulators of cytokine receptor signaling via the Janus kinase signal transducer and activation of transcription pathway (the JAK STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal transducing

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