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GLI-3 Polyclonal Antibody, 50ul Dry Bath The protein encoded by LIG4

SKU: 72021623711

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GLI-3 Polyclonal Antibody, 50ul Dry Bath The protein encoded by LIG4GLI3 encodes GLI family zinc finger 3 which belongs to the C2H2 type zinc finger proteins subclass of the Gli family. They are characterized as DNA binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated

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Description

The protein encoded by LIG4 is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction

and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching

Zinc finger CCCH domain-containing protein 8 acts as a transcriptional repressor of the GATA3 promoter

The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase

GLI-3 Polyclonal Antibody, 50ul Dry Bath The protein encoded by LIG4GLI3 encodes GLI family zinc finger 3 which belongs to the C2H2 type zinc finger proteins subclass of the Gli family. They are characterized as DNA binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated

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