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MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The epsilon globin gene (HBE)

SKU: 71914629149

4.8
USD142.00 USD162.00

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MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The epsilon globin gene (HBE)MDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I

As a monomer

PIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family

SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al

MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The epsilon globin gene (HBE)MDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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