ARHGAP11A Polyclonal Antibody, 100ul Peptide Synthesis induction:Down-regulated in cancer pancreatic cells

induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis

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suggesting an important role of this protein during integrin-dependent cell adhesion

The proteins mediate signal transduction events that play a role in the regulation of cell development

ARHGAP11A Polyclonal Antibody, 100ul Peptide Synthesis induction:Down-regulated in cancer pancreatic cellsGTPase activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras related proteins, resulting in downregulation of their active form. ARHGAP11A (Rho GTPase activating protein 11A), also known as KIAA0013 or MGC70740, is a 1,023 amino acid protein that contains one helical Rho GAP domain and is encoded by a gene located on human chromosome 15. Defects in the gene encoding ARHGAP11A may cause mental retardation. Human chromosome