Gab 1 Polyclonal Antibody, 100ul[BT-AP03408] Polyclonal Antibodies The protein encoded by this

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II)| which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation

653 bases and maps to human chromosome 2q14

Mutations in ATP7A are associated with Menkes disease

The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1

Gab 1 Polyclonal Antibody, 100ul[BT-AP03408] Polyclonal Antibodies The protein encoded by thisThe GRB2 associated binding protein 1 encoded by GAB1 is a member of the IRS1 like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.