Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration Plays an important role in

Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs

This gene is located within the Smith-Magenis syndrome region on chromosome 17

it is a ligand for cell surface G protein-coupled receptors

It binds mutliple lipid-containing molecules| including phosphatidylserine| phosphatidylinositol 4-phosphate (PI4P) and oxysterol| and promotes their exchange between the endoplasmic reticulum and the plasma membrane

Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration Plays an important role inThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.