Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library The extracellular portion of the

The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation

The encoded protein product is a preproprotein

FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death

An important paralog of this gene is LONP1

Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library The extracellular portion of theMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.