Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter The protein functions in cap-independent

The protein functions in cap-independent translation of ornithine decarboxylase mRNA

This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I)

and axon fasciculation

This gene is aberrantly methylated in pancreatic cancer

Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter The protein functions in cap-independentThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.