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Mouse Dickkopf-related Protein 1, DKK1 ELISA Kit, 96T Human Genome Knockout Libraries tissue specificity:Detected in brain and

SKU: 70909281827

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Mouse Dickkopf-related Protein 1, DKK1 ELISA Kit, 96T Human Genome Knockout Libraries tissue specificity:Detected in brain andAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6 (PubMed: 18524778). Inhibits the pro apoptotic function of KREMEN1 in a Wnt independent manner, and has anti apoptotic activity (PubMed: 26206087). Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning

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Description

tissue specificity:Detected in brain and spinal cord

a neck domain that interacts with other proteins

and may contribute to the multidrug resistance phenomenon

This nuclear protein functions as a trimethylation-specific demethylase

Mouse Dickkopf-related Protein 1, DKK1 ELISA Kit, 96T Human Genome Knockout Libraries tissue specificity:Detected in brain andAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6 (PubMed: 18524778). Inhibits the pro apoptotic function of KREMEN1 in a Wnt independent manner, and has anti apoptotic activity (PubMed: 26206087). Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning

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