Karyopherin Alpha2 Polyclonal Antibody, 100ul Gene Editing Cofactors B and E can

Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers

form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors

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Karyopherin Alpha2 Polyclonal Antibody, 100ul Gene Editing Cofactors B and E canThe import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy independent docking of the protein to the nuclear envelope and the second is an energy dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in