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MYBPC3 Polyclonal Antibody, 100ul Mechanical Pipette Many alternatively spliced transcript variants

SKU: 70377969209

4.2
EUR141.00 EUR165.00

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MYBPC3 Polyclonal Antibody, 100ul Mechanical Pipette Many alternatively spliced transcript variantsMYBPC3 encodes the cardiac isoform of myosin binding protein C. Myosin binding protein C is a myosin associated protein found in the cross bridge bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction.

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Description

Many alternatively spliced transcript variants encoding different isoforms have been described for this gene

and polymorphisms that alter expression of this gene may play a role in carcinogenesis

Contains 1 SAM (sterile alpha motif) domain

Cofactor D is one of four proteins (cofactors A| D| E| and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates

MYBPC3 Polyclonal Antibody, 100ul Mechanical Pipette Many alternatively spliced transcript variantsMYBPC3 encodes the cardiac isoform of myosin binding protein C. Myosin binding protein C is a myosin associated protein found in the cross bridge bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction.

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