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Mesothelin Rabbit Polyclonal Antibody, 20ul Cell Biology Reciprocal translocations between chromosomes 22

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Mesothelin Rabbit Polyclonal Antibody, 20ul Cell Biology Reciprocal translocations between chromosomes 22This gene encodes a preproprotein that is proteolytically processed to generate two protein products megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol anchored cell surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas

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Description

Reciprocal translocations between chromosomes 22 and 17

-delta and -epsilon

platelet dense granules

This complex translocates to the nucleus and activates the transcription of interferons alpha and beta

Mesothelin Rabbit Polyclonal Antibody, 20ul Cell Biology Reciprocal translocations between chromosomes 22This gene encodes a preproprotein that is proteolytically processed to generate two protein products megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol anchored cell surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas

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