S4A7 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Mutations in this gene are

Mutations in this gene are associated with venous thrombosis

SFTPB encodes the pulmonary-associated surfactant protein B (SPB)

It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains

The protein may play an important role in the epigenetic control of chromatin structure and gene expression

S4A7 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Mutations in this gene areThis locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1: 1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.