Akt1 Polyclonal Antibody, 100ul[BT-AP00346] Cell Culture The encoded protein is a

The encoded protein is a member of the BCL-2 family of cell death regulators

XRN2 encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites

whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation

The protein thus belongs to the suppressor of cytokine signaling (SOCS)

Akt1 Polyclonal Antibody, 100ul[BT-AP00346] Cell Culture The encoded protein is aThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a