CCBE1 Polyclonal Antibody, 50ul Biochemical Reagents CDKN2A (cyclin dependent kinase inhibitor

CDKN2A (cyclin dependent kinase inhibitor 2A) generates several transcript variants which differ in their first exons

act as an integration point for multiple biochemical signals

Alternative splicing of TAF1 results in multiple transcript variants

and this activation is strictly dependent on an intact T1R1+3 heterodimer

CCBE1 Polyclonal Antibody, 50ul Biochemical Reagents CDKN2A (cyclin dependent kinase inhibitorThis gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia lymphedema syndrome, a generalized lymphatic dysplasia in humans.