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AAT Polyclonal Antibody, 50ul[BT-AP00075] Culture Media This gene is located within

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AAT Polyclonal Antibody, 50ul[BT-AP00075] Culture Media This gene is located withinAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

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Description

This gene is located within a large protease gene cluster on chromosome 16

Two transcript variants encoding the same pr

was significantly upregulated in human monocytes exposed to interferon alpha

The recombination activating gene 1 component is thought to contain most of the catalytic activity

AAT Polyclonal Antibody, 50ul[BT-AP00075] Culture Media This gene is located withinAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

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