NPL4 Polyclonal Antibody, 20ul Reservoirs The protein encoded by BAD

The protein encoded by BAD (BCL2 associated agonist of cell death) is a member of the BCL-2 family

Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products

Shb (SH2 domain-containing adapter protein b)

and thus may define a distinct family of cyclin-dependent kinase activating proteins

NPL4 Polyclonal Antibody, 20ul Reservoirs The protein encoded by BADBinds ubiquitinated proteins via its RanBP2 type zinc finger.,The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4 UFD1L VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.,pathway: Protein degradation;