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VMAT2 Polyclonal Antibody, 20ul Bottles The protein encoded by ARHGEF5

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VMAT2 Polyclonal Antibody, 20ul Bottles The protein encoded by ARHGEF5The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al.,

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Description

The protein encoded by ARHGEF5 (Rho guanine nucleotide exchange factor 5) may form a complex with G proteins and stimulate Rho-dependent signals

Mutations of this class mu gene have been linked with a slight increase in a number of cancers| likely due to exposure with environmental toxins

GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines

Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory

VMAT2 Polyclonal Antibody, 20ul Bottles The protein encoded by ARHGEF5The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al.,

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