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Ku-70 (Acetyl Lys539) Polyclonal Antibody, 50ul Filtration It is inactive against free

SKU: 68140451860

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Ku-70 (Acetyl Lys539) Polyclonal Antibody, 50ul Filtration It is inactive against freeThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

It is inactive against free core histones

Mutations and deletions in NKX2-1 are associated with benign hereditary chorea

This gene encodes one of testis-specific transcription factors which are essential for spermatogenesis| oogenesis and folliculogenesis

developmental stage:Expressed in all fetal tissues examined

Ku-70 (Acetyl Lys539) Polyclonal Antibody, 50ul Filtration It is inactive against freeThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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