p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11723] Lysosome Three transcript variants encoding three

Three transcript variants encoding three different isoforms have been found for this gene

Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity)

indicating a potential role for this protein in DNA repair

which does not change the protein sequence

p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11723] Lysosome Three transcript variants encoding threeThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative