Human Dynein Heavy Chain 17, Axonemal, DNAH17 ELISA Kit, 96T Mammalian Expression Mutations in this gene cause

Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6

Transcripts of this gene have been reported in specimens of human testis

This gene encodes a guanosine triphosphatase enzyme

An important paralog of this gene is LSAMP

Human Dynein Heavy Chain 17, Axonemal, DNAH17 ELISA Kit, 96T Mammalian Expression Mutations in this gene causeForce generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force producing power stroke is thought to occur on release of ADP (Probable). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating (PubMed: 31178125).