TAF II p140 Polyclonal Antibody, 50ul Endonucleases & Exonucleases Alpha-A and alpha-B gene products

Alpha-A and alpha-B gene products are differentially expressed

It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner

Alternatively spliced transcript variants encoding different isoforms have been described for CNTROB

The protein encoded by this gene contains a PDZ domain

TAF II p140 Polyclonal Antibody, 50ul Endonucleases & Exonucleases Alpha-A and alpha-B gene productsThe highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box binding protein (TBP; MIM 600075) and a set of TBP associated factors (TAFs), including TAF3 (TATA box binding protein associated factor 3). TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors.