Vav(Phospho Tyr160) Polyclonal Antibody, 100ul Low retention tips despite its location within a

despite its location within a region of imprinted genes on chromosome 11

The TRIM motif includes zinc-binding domains| a RING finger region| a B-box motif and a coiled-coil domain

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Vav(Phospho Tyr160) Polyclonal Antibody, 100ul Low retention tips despite its location within aThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.