EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression The protein encoded by ELK1

The protein encoded by ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade

a gene expressed in the head and limbs of the developing fruit fly

Mutations in this gene are associated with erythrocytosis familial type 4

cell division

EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression The protein encoded by ELK1EPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce