Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression It is an intronless gene

It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines| suggesting that it may play a role in lung tumorigenesis

Component of the cornified envelope of keratinocytes

cleaves SPHK2 which is released from cells and remains enzymatically active extracellularly

Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy

Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression It is an intronless geneSeems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.