S5A2 Polyclonal Antibody, 100ul Antibody Humanization The SART1(259) protein possesses tumor

The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients

Alternative splicing of this gene results in two transcript variants

miscellaneous:'Reprimo' signifies stop/repress

Mutations in this gene result in colobomata

S5A2 Polyclonal Antibody, 100ul Antibody Humanization The SART1(259) protein possesses tumorThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).