TFPI Polyclonal Antibody, 50ul Cell Transfection endonuclease catalytic subunit encoded by

endonuclease catalytic subunit encoded by ERCC4 forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair

The expression of this DNA binding protein is upregulated by transcription factor p53

and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa

It is found in mitochondria| peroxisomes| and the cytoplasm

TFPI Polyclonal Antibody, 50ul Cell Transfection endonuclease catalytic subunit encoded byTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.