VPS35 Polyclonal Antibody, 100ul Isothermal Amplification Mutations in ACVR1B are associated

Mutations in ACVR1B are associated with pituitary tumors

This protein may play an important role in both nuclear and mitochondrial base excision repair

Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect

Multiple cysteine residues are necessary for proper targeting to the plasma membrane

VPS35 Polyclonal Antibody, 100ul Isothermal Amplification Mutations in ACVR1B are associatedVPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and