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IL-3R Alpha Polyclonal Antibody, 50ul Bacterial Expression The encoded mechanosensing protein contains

SKU: 67048502594

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IL-3R Alpha Polyclonal Antibody, 50ul Bacterial Expression The encoded mechanosensing protein containsInterleukin 3 receptor subunit alpha encoded by IL3RA is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2 GM CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand

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Description

The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension| resulting in the reconfiguration of cadherin-actin filament connections

Mutations have been associated with X-linked dyskeratosis congenita

Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis

This gene encodes a protein with two leucine zipper domains

IL-3R Alpha Polyclonal Antibody, 50ul Bacterial Expression The encoded mechanosensing protein containsInterleukin 3 receptor subunit alpha encoded by IL3RA is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2 GM CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand

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