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TM165 Rabbit Polyclonal Antibody, 100ul Sample Library Tubes Junction-mediating and -regulatory protein acts

SKU: 66986692328

4.4
PLN123.75 PLN156.75

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TM165 Rabbit Polyclonal Antibody, 100ul Sample Library Tubes Junction-mediating and -regulatory protein actsThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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Description

Junction-mediating and -regulatory protein acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions

is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense

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TM165 Rabbit Polyclonal Antibody, 100ul Sample Library Tubes Junction-mediating and -regulatory protein actsThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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