Stat3 Polyclonal Antibody, 20ul[BT-AP14539] Drying & Desiccation The protein encoded by this

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

and is overexpressed in the tumors of various epithelial cancers

stabilizes the FRAP1-RAPTOR interaction and favors RAPTOR-mediated inhibition of FRAP1 activity

The protein is thought to play a role in protecting against the proteases leaking from lysosomes

Stat3 Polyclonal Antibody, 20ul[BT-AP14539] Drying & Desiccation The protein encoded by thisThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and