TRAF7 Polyclonal Antibody, 50ul Enzymes The activity of this receptor

The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system

Mutations in this gene result in pseudohypoaldosteronism type IIB

The product of this reaction is glucosylceramide

|tissue specificity:Detected in spleen and thyroid| and at lower levels in kidney| brain| lung and pancreas

TRAF7 Polyclonal Antibody, 50ul Enzymes The activity of this receptorTumor necrosis factor (TNF; see MIM 191160) receptor associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N terminal cysteine histidine rich region containing zinc RING and or zinc finger motifs; a coiled coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self association and receptor binding.