PHLP1 Polyclonal Antibody, 100ul Cell fragmentation and collection SFRPs act as soluble modulators

SFRPs act as soluble modulators of Wnt signaling

cell death

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

Dimerization with other BHLH proteins is required for efficient DNA binding

PHLP1 Polyclonal Antibody, 100ul Cell fragmentation and collection SFRPs act as soluble modulatorsThis gene encodes a member of the serine threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt mediated insulin signaling.