Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis The interaction with ERC1 may

The interaction with ERC1 may be mediated by PHLDB2

which further interacts with the other family members

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

Members of HES6 family regulate cell differentiation in numerous cell types

Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis The interaction with ERC1 mayVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.