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OAZ2 Polyclonal Antibody, 20ul Cell Dissociation The VCX gene cluster is

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OAZ2 Polyclonal Antibody, 20ul Cell Dissociation The VCX gene cluster isThe protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This

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Description

The VCX gene cluster is polymorphic in terms of copy number

Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported| but the full-length nature and biological validity of some variants have not been defined

The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding

An important paralog of this gene is GSDMD

OAZ2 Polyclonal Antibody, 20ul Cell Dissociation The VCX gene cluster isThe protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This

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