Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression This cytokine has been found

This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen

This protein may function in vesicle trafficking| membrane fusion| protein complex assembly and cell motility

and peripheral blood leukocytes

Mutations inCSF1R have been associated with a predisposition to myeloid malignancy

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression This cytokine has been foundMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.