FRP-2 Polyclonal Antibody, 50ul Microbial Genome Editing The product of this gene

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

Unlike the other two isoforms| p46Shc is targeted to the mitochondrial matrix

and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses

it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins

FRP-2 Polyclonal Antibody, 50ul Microbial Genome Editing The product of this geneSFRP2 encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of SFRP2 is a potential marker for the presence of colorectal cancer.