PKHA1 Polyclonal Antibody, 100ul Tubes The activity of this protein

The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine

It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

2| has been defined by analysis of patients with partial trisomy 21

DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al

PKHA1 Polyclonal Antibody, 100ul Tubes The activity of this proteinThis gene encodes a pleckstrin homology domain containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4 bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this