ETAR Polyclonal Antibody, 100ul[BT-AP03093] Organelle Studies The protein encoded by this

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription

Through its expression in dendritic cells

granule enzyme release

may mediate vesicle trafficking steps in the endosome/lysosome pathway

ETAR Polyclonal Antibody, 100ul[BT-AP03093] Organelle Studies The protein encoded by thisEDNRA encodes the receptor for endothelin 1, a peptide that plays a role in potent and long lasting vasoconstriction. This receptor associates with guanine nucleotide binding (G) proteins, and this coupling activates a phosphatidylinositol calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.