PYK2 Monoclonal Antibody, 50ul[BT-MCA1077] Metabolic enzymes tool compounds Erb-b2 receptor tyrosine kinase 2

Erb-b2 receptor tyrosine kinase 2 has no ligand binding domain of its own and therefore cannot bind growth factors

Member of the FGF family possess broad mitogenic and cell survival activities

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The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits

PYK2 Monoclonal Antibody, 50ul[BT-MCA1077] Metabolic enzymes tool compounds Erb-b2 receptor tyrosine kinase 2This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and