Rock-2 Polyclonal Antibody, 100ul[BT-AP07971] Enzyme Activity Assays Mutations in this gene are

Mutations in this gene are a cause of the H-Bombay blood group

an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline

Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands

and in subcellular localization

Rock-2 Polyclonal Antibody, 100ul[BT-AP07971] Enzyme Activity Assays Mutations in this gene areRho associated protein kinase 2 encoded by ROCK2 is a serine threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.