PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07140] Miscellaneous Calcineurin like EF-hand protein 2

Calcineurin like EF-hand protein 2 shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway

Inhibition of this protein's activity may confer anticancer benefits

This gene encodes a member of the receptor tyrosine kinase family of proteins

Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process

PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07140] Miscellaneous Calcineurin like EF-hand protein 2Phosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1