PCBP2 Polyclonal Antibody, 20ul Nucleic Acid Extraction internalizes and degrades oxidized low-density

internalizes and degrades oxidized low-density lipoprotein

Although the gene has been reported to be on chromosome 15| this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

leading to the dephosphorylation of Cdc2 in the late G2 phase

PCBP2 Polyclonal Antibody, 20ul Nucleic Acid Extraction internalizes and degrades oxidized low-densityThe protein encoded by this gene appears to be multifunctional. Along with PCBP 1 and hnRNPK, it is one of the major cellular poly(rC) binding proteins. The encoded protein contains three K homologous (KH) domains which may be involved in RNA binding. Together with PCBP 1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence specific interaction with stem loop IV of the IRES, promoting poliovirus RNA replication